# Ep. 186: The Biology of Binge Eating: New Research on How Weight Suppression Impacts Leptin and GLP-1 (with Pamela Keel, PhD) Page: https://stenobird.com/podcast/brain-over-binge-podcast-221294/ep-186-the-biology-of-binge-eating-new-research-on-how-weight-suppression-impacts-leptin-and-glp-1-with-pamela-keel-phd Text version: https://stenobird.com/podcast/brain-over-binge-podcast-221294/ep-186-the-biology-of-binge-eating-new-research-on-how-weight-suppression-impacts-leptin-and-glp-1-with-pamela-keel-phd.md Podcast: [Brain over Binge Podcast](https://stenobird.com/podcast/brain-over-binge-podcast-221294) Published: 2025-08-27T23:31:00+00:00 Episode link: https://brainoverbinge.com/ep-186-the-biology-of-binge-eating-new-research-on-how-weight-suppression-impacts-leptin-and-glp-1-pamela-keel/ Audio file: https://dts.podtrac.com/redirect.mp3/traffic.libsyn.com/secure/brainoverbinge/bob186-PamelaKeel1.mp3?dest-id=4102680 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/brain-over-binge-podcast-221294/episodes/ep-186-the-biology-of-binge-eating-new-research-on-how-weight-suppression-impacts-leptin-and-glp-1-with-pamela-keel-phd Duration seconds: 3079 ## Resource I talked with Dr. Pamela Keel about her new study exploring the biological underpinnings of binge eating. We discuss how weight suppression affects key hormones—GLP‑1 and leptin—and how those changes can reduce satiety and drive binge eating. Dr. Keel explains what this means for understanding urges, recovery, and weight restoration—and we also discuss the potential role and risks of GLP‑1 medications in treatment. Learn more about Pamela Keel and her new study: FSU researcher’s new findings connect biological and behavioral consequences of weight loss to binge eating Pamela Keel, PhD Brain over Binge resources: Get the FREE 30-day Inspiration Booklet Get personalized support with one-on-one coaching or group coaching Subscribe to the Brain over Binge Course for only $18.99 per month Get the Second Edition of Brain over Binge on Amazon and Audible , BarnesandNoble.com , Apple iBooks , or Kobo . Get the Brain over Binge Recovery Guide Disclaimer: *The Brain over Binge Podcast is produced and recorded by Brain over Binge Recovery Coaching, LLC. All work is copyrighted by Brain over Binge Recovery Coaching, LLC, and all rights are reserved. As a disclaimer, the hosts of the Brain over Binge Podcast are not professional counselors or licensed healthcare providers, and this podcast is not a substitute for medical advice or any form of professional therapy. Eating disorders can have serious health consequences and you are strongly advised to seek medical attention for matters relating to your health. Please get help when you need it, and good luck on your journey. ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/brain-over-binge-podcast-221294/episodes/ep-186-the-biology-of-binge-eating-new-research-on-how-weight-suppression-impacts-leptin-and-glp-1-with-pamela-keel-phd/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/brain-over-binge-podcast-221294/ep-186-the-biology-of-binge-eating-new-research-on-how-weight-suppression-impacts-leptin-and-glp-1-with-pamela-keel-phd.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.