# Episode 59. Management of Systemic Mastocytosis with Dr. Daniel DeAngelo

Page: https://stenobird.com/podcast/blood-cancer-talks-5570002/episode-59-management-of-systemic-mastocytosis-with-dr-daniel-deangelo
Text version: https://stenobird.com/podcast/blood-cancer-talks-5570002/episode-59-management-of-systemic-mastocytosis-with-dr-daniel-deangelo.md
Podcast: [Blood Cancer Talks](https://stenobird.com/podcast/blood-cancer-talks-5570002)
Published: 2025-05-08T11:00:00+00:00
Episode link: https://share.transistor.fm/s/589af0c1
Audio file: https://media.transistor.fm/589af0c1/80418ce5.mp3
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JSON: https://stenobird.com/v1/public/podcasts/blood-cancer-talks-5570002/episodes/episode-59-management-of-systemic-mastocytosis-with-dr-daniel-deangelo
Duration seconds: 3798

## Resource

In this episode, we discussed the management of systemic mastocytosis with Dr. Daniel DeAngelo from the Dana Farber Cancer Institute. Here are the key studies we discussed: Midostaurin https://www.nejm.org/doi/10.1056/NEJMoa1513098?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200www.ncbi.nlm.nih.gov Avapritinib EXLPORER study: https://www.nature.com/articles/s41591-021-01538-9 PATHFINDER study: https://www.nature.com/articles/s41591-021-01539-8 Bezuclastinib: APEX trial: https://ashpublications.org/blood/article/144/Supplement%201/659/530240/Apex-Part-1-Updated-Assessment-of-Bezuclastinib HSCT for Advanced SM: https://ascopubs.org/doi/10.1200/JCO.2014.55.2018

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## Transcript

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