# Antidepressants in pregnancy: A closer look at miscarriage risk

Page: https://stenobird.com/podcast/bjgp-interviews-1317540/antidepressants-in-pregnancy-a-closer-look-at-miscarriage-risk
Text version: https://stenobird.com/podcast/bjgp-interviews-1317540/antidepressants-in-pregnancy-a-closer-look-at-miscarriage-risk.md
Podcast: [BJGP Interviews](https://stenobird.com/podcast/bjgp-interviews-1317540)
Published: 2025-11-04T07:00:00+00:00
Episode link: https://bjgplife.com/antidepressants-in-pregnancy-a-closer-look-at-miscarriage-risk
Audio file: https://episodes.captivate.fm/episode/e43b1283-cc30-46be-8c6b-a009d14a2fff.mp3
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JSON: https://stenobird.com/v1/public/podcasts/bjgp-interviews-1317540/episodes/antidepressants-in-pregnancy-a-closer-look-at-miscarriage-risk
Duration seconds: 572

## Resource

Today, we’re speaking to Flo Martin, an honorary research associate at the University of Bristol. Title of paper: First trimester antidepressant use and miscarriage: a comprehensive analysis in the Clinical Practice Research Datalink GOLD Available at: https://doi.org/10.3399/BJGP.2025.0092 Antidepressant use during pregnancy is rising, with concerns from pregnant women that these medications may increase the risk of miscarriage if taken prenatally. Evidence is conflicting so we used the Clinical Practice Research Datalink, a large repository of UK-based primary care data, and a range of methods to investigate antidepressant use during trimester one and risk of miscarriage. Transcript This transcript was generated using AI and has not been reviewed for accuracy. Please be aware it may contain errors or omissions. Speaker A 00:00:00.240 - 00:00:52.800 Hello and welcome to BJJP Interviews. I'm Nada Khan and I'm one of the associate editors at the bjgp. Thanks for taking the time today to listen to this podcast. In today's episode, we're speaking to Dr. Flo Martin, an honorary research associate at the University of Bristol. We're here to look at the paper she's recently published here in the BJGP titled First Trimester Antidepressant Use and Miscarriage A Comprehensive Analysis in the Clinical Practice Research Data Link. Gold. So, hi, Flo, it's great to meet you and talk about this research. And I think this paper touches on an area that clinicians and women often approach with a bit of uncertainty, just in terms of prescribing safety, really, in pregnancy in general. But can you talk us through what we know already about prescribing for antidepressants and risk in pregnancy, just to frame what you've done here? Speaker B 00:00:53.280 - 00:02:22.860 Yeah, absolutely. So…

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## Transcript

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