# David Liu: Performing Chemistry on DNA to Unlock Personalized Gene Editing Page: https://stenobird.com/podcast/behind-the-breakthroughs-7055075/david-liu-performing-chemistry-on-dna-to-unlock-personalized-gene-editing Text version: https://stenobird.com/podcast/behind-the-breakthroughs-7055075/david-liu-performing-chemistry-on-dna-to-unlock-personalized-gene-editing.md Podcast: [Behind the Breakthroughs](https://stenobird.com/podcast/behind-the-breakthroughs-7055075) Published: 2025-08-20T07:00:00+00:00 Episode link: https://shows.acast.com/behind-the-breakthroughs-by-inside-precision-medicine/episodes/david-liu-performing-chemistry-on-dna-to-unlock-personalized Audio file: https://sphinx.acast.com/p/open/s/67105af848726944170ab1fe/e/68a4dffc457a24bb9581e226/media.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/behind-the-breakthroughs-7055075/episodes/david-liu-performing-chemistry-on-dna-to-unlock-personalized-gene-editing Duration seconds: 3354 ## Resource David R. Liu, PhD, Harvard and Broad Institute professor, invented base and prime editing—gene editing tools now in 20+ clinical trials with early wins against sickle cell, leukemia, and more. Founder of Editas, Beam, and Prime Medicine, and winner of the 2025 Breakthrough Prize, Liu joins Behind The Breakthroughs to share how chemistry and evolution are driving the next wave of medicine. Produced and hosted by Jonathan D. Grinstein, PhD Audio mixed and mastered by David Mosely Brought to you by Inside Precision Medicine (SAGE Publishing) Hosted on Acast. See acast.com/privacy for more information. ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/behind-the-breakthroughs-7055075/episodes/david-liu-performing-chemistry-on-dna-to-unlock-personalized-gene-editing/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/behind-the-breakthroughs-7055075/david-liu-performing-chemistry-on-dna-to-unlock-personalized-gene-editing.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.