# Amber Salzman: Epigenetic Editing Aims to Refine Personalized Genetic Medicine Page: https://stenobird.com/podcast/behind-the-breakthroughs-7055075/amber-salzman-epigenetic-editing-aims-to-refine-personalized-genetic-medicine Text version: https://stenobird.com/podcast/behind-the-breakthroughs-7055075/amber-salzman-epigenetic-editing-aims-to-refine-personalized-genetic-medicine.md Podcast: [Behind the Breakthroughs](https://stenobird.com/podcast/behind-the-breakthroughs-7055075) Published: 2025-07-23T07:00:00+00:00 Episode link: https://shows.acast.com/behind-the-breakthroughs-by-inside-precision-medicine/episodes/uncut-gems-epigenetic-editing-aims-to-refine-personalized-ge Audio file: https://sphinx.acast.com/p/open/s/67105af848726944170ab1fe/e/688055b9498abee416ef990a/media.mp3 Processing state: not_requested JSON: https://stenobird.com/v1/public/podcasts/behind-the-breakthroughs-7055075/episodes/amber-salzman-epigenetic-editing-aims-to-refine-personalized-genetic-medicine Duration seconds: 2457 ## Resource With recent safety setbacks in gene therapy underscoring the risks of genetic medicine, Amber Salzman, PhD, is charting a different course. After 25 years in big pharma, she now leads Epicrispr, where their Gene Expression Modulation System (GEMS) fine-tunes gene activity to tackle diseases too complex for traditional gene replacement, including Duchenne muscular dystrophy. On Behind the Breakthroughs , Salzman shares how epigenomic modulation could open new frontiers in treatment. Produced and hosted by Jonathan D. Grinstein, PhD Audio mixed and mastered by David Mosely Brought to you by Inside Precision Medicine (SAGE Publishing) Hosted on Acast. See acast.com/privacy for more information. ## Actions - request_transcript: `POST https://stenobird.com/v1/public/podcasts/behind-the-breakthroughs-7055075/episodes/amber-salzman-epigenetic-editing-aims-to-refine-personalized-genetic-medicine/transcription-requests` — Idempotently request low-priority transcript generation for this episode. - read_markdown: `GET https://stenobird.com/podcast/behind-the-breakthroughs-7055075/amber-salzman-epigenetic-editing-aims-to-refine-personalized-genetic-medicine.md` — Read the agent-friendly Markdown representation of this episode resource. A page view does not enqueue transcription. Agents should invoke `request_transcript` explicitly when they need this episode processed. ## Transcript Full transcripts are not published on public pages unless there is a clear rights basis.