# De-Extinction: A Scientist’s Perspective from Inside a Cloning Lab

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Text version: https://stenobird.com/podcast/all-creatures-podcast-669262/de-extinction-a-scientist-s-perspective-from-inside-a-cloning-lab.md
Podcast: [All Creatures Podcast](https://stenobird.com/podcast/all-creatures-podcast-669262)
Published: 2026-04-01T08:05:00+00:00
Episode link: https://www.podtrac.com/pts/redirect.mp3/pdst.fm/e/tracking.swap.fm/track/YfZO4tERxneauNcW9Fgn/mgln.ai/e/211/traffic.megaphone.fm/ARML1741459467.mp3?updated=1774991419
Audio file: https://www.podtrac.com/pts/redirect.mp3/pdst.fm/e/tracking.swap.fm/track/YfZO4tERxneauNcW9Fgn/mgln.ai/e/211/traffic.megaphone.fm/ARML1741459467.mp3?updated=1774991419
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Duration seconds: 3496

## Resource

Chris draws on his PhD-era experience at Texas A&M—including meeting Dewey, the world’s first cloned deer—to unpack de-extinction and why cloning is far harder and less efficient than headlines suggest. He revisits Dolly’s breakthrough, explains somatic cell nuclear transfer, and highlights low success rates and frequent abnormalities. Chris explores the only true de-extinction attempt, the Pyrenean ibex, which survived only minutes, and explains why mammoths and “dire wolves” cannot be truly cloned due to fragmented DNA, with current efforts relying instead on genetic engineering. Chris also outlines major challenges around elephant egg sourcing, embryo transfer, and gestation, questions claims that mammoths could meaningfully impact climate change, and argues conservation resources are better directed toward protecting existing species, while acknowledging potential scientific benefits from the research. Timeline 00:00 Podcast Intro and De-Extinction 00:38 Meeting Dewey the Clone 03:31 Cloning Hype vs Reality 05:06 Elephant Repro Research Shift 07:02 Dolly and Cell Reset 10:22 How Cloning Works 15:46 Lab Data on Efficiency 20:50 De-Extinction Case Study Ibex 22:32 Why Mammoths Aren't Clones 26:40 Elephant Surrogates and Obstacles 30:36 Elephant Egg Retrieval 31:43 Lab Grown Gametes 32:33 Embryo Transfer Challenges 33:01 Welfare and Ethics 34:26 Climate Claims Debunked 36:28 Funding Priorities Debate 38:50 Real Conservation Wins 40:07 False Tech Fix Narrative 42:58 Forest Elephants Solution 47:01 Moonshot Case for Science 49:57 What De Extinction Delivers 52:02 Choose Protection Today =========================================================== Another thank you to all our Patreon supporters. You too can join for one cup of "good" coffee a month. With your pledge y…

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